Base de dados : HANSEN
Pesquisa : DISTRIBUICAO DE QUI-QUADRADO [Descritor de assunto]
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Id:23183
Autor:Boggild, Andrea K; Correia, Jason D; Keystone, Jay S; Kain, Keven C
Título:Leprosy in Toronto: an analysis of 184 imported cases
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Fonte:s.l; s.n; Jan. 2004. 5 p. tab.
Resumo:BACKGROUND: Leprosy is a rare but serious mycobacterial infection. Immigration from areas where the disease is endemic has resulted in the importation of leprosy into countries where it is not endemic and where physicians and health care workers have little or no experience in diagnosis and therapy. In this study we characterized leprosy patients seen in a tropical disease unit that manages most of the reported leprosy cases in Canada. METHODS: We reviewed the clinical records of all 184 leprosy patients who were referred to the Tropical Disease Unit at Toronto General Hospital between 1979 and 2002 and abstracted demographic and clinical information. RESULTS: Patients were more likely to be male (122 or 66.3%) and of Indian (44 or 23.9%), Filipino (49 or 26.6%) or Vietnamese (37 or 20.1%) origin. Patients experienced symptoms for a mean of 4.8 years before referral to the Tropical Disease Unit. Most had no family history of leprosy (152/172 or 88.4%). Most patients presented with either borderline tuberculoid (80 or 43.5%) or borderline lepromatous (37 or 20.1%) disease. On average, patients presented with 5.8 skin lesions. Upper- and lower-extremity nerve dysfunction was common at presentation, with up to one-third of patients demonstrating either sensory or motor loss. A significantly greater lag time to presentation was observed in patients who emigrated from low-prevalence regions (p < 0.001). INTERPRETATION: Leprosy is a chronic infectious disease that is associated with serious morbidity if left untreated. Leprosy is uncommon in developed countries, but it is important for physicians to have a high index of suspicion when a foreign-born patient presents with chronic dermatitis and peripheral nerve involvement. (AU).
Descritores:Análise de Variância
Distribuição de Qui-Quadrado
Migração Internacional
Índia/EH
Hanseníase/*EP
Ontario/EP
Filipinas/EH
População Urbana
Vietnã/EH
Limites:HUMANO
MASCULINO
FEMININO
ADULTO
MEIA-IDADE
Localização:BR191.1; 09327/s


  2 / 7 HANSEN  
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Id:18558
Autor:Keita, S; Tiendrebeogo, A; Berthe, D; Faye, O; N'diaye, H. T
Título:Valeur prédictive des motifs de consultation pour le diagnostic de lèpre à Bamako (Mali)
Predictive value of medical reasons in the diagnosis of leprosy in Bamako (Mali)-
Fonte:s.l; s.n; 2002. 3 p. tab.
Resumo:INTRODUCTION: One of the weak points in the strategy for eliminating leprosy is the poor quality of screening. To overcome this, the World Health Organization (WHO) encourages endemic countries to run campaigns for the elimination of leprosy by circulating educational messages and mobilizing the medical community for early screening of cases. The aim of our study was to identify the motives for consultation with high predictive value for the diagnosis of leprosy and to determine the late diagnosis factors and hence assist the staff on site to improve the results of their leprosy elimination campaigns. PATIENTS AND METHODS: The study consisted, during the second trimester of 1999, in interviewing all the patients consulting for the first time the Marchoux Institute or the units screening for leprosy in the Bamako area. The interview recorded the motives for consultation, the delay before consulting and the reasons for late consulting. To assess their positive predictive value, the motives for consultation were related to the diagnosis retained (leprosy or not). RESULTS: One thousand one hundred and seventy seven patients were interviewed. The motive for consulting, "suspected leprosy", scored the highest positive predictive value (PPV) (80 p. 100): 12 cases of leprosy were diagnosed by 15 consultants having suspected leprosy. Neurological problems were the second motive for consultation (PPV=61.9 p. 100). The most frequent motive for consultation was spots or "macules" (20 p. 100 of consultations), but only provided a positive predictive value of 19 p. 100. Prior consultations and non-specialized treatments were identified as factors of delay in diagnosing leprosy (P<0.001). CONCLUSIONS: Diagnosis of leprosy cannot be based on the motives for dermatological consultation alone. The macules are the most apparent signs, but of low predictive value. Nevertheless, they are an early but non-specific sign of leprosy and are often neglected by the patient. Other than macules, attention must be paid to the neurological signs (dysesthesia, motor disorders) when screening for leprosy. These signs may appear early on, or be observed at a late stage in the progression of the disease. (AU).
Descritores:ANALISE DE VARIANCIA
DISTRIBUICAO DE QUI-QUADRADO
INTERPRETACAO ESTATISTICA DE DADOS
DIAGNOSTICO DIFERENCIALRESUMO EM INGLES
HANSENIASE/*DI/PC
FATORES DE TEMPO
ORGANIZACAO MUNDIAL DA SAUDE
Limites:ADOLESCENTE
ADULTO
IDOSO
IDOSO DE 80 ANOS OU MAIS
CRIANCA
PRE-ESCOLAR
ESTUDO COMPARATIVO
RESUMO EM INGLES
HUMANO
LACTENTE
RECEM-NASCIDO
MEIA-IDADE
Localização:BR191.1; 09071/s


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Id:15476
Autor:Bansal, Rakesh; Garg, Bhagat R; Adithan, C; Vasireddit, Srinivas S; Kumar, Vijay; Chandra, Dinesh
Título:Cortisol status in different types of leprosy
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Fonte:s.l; s.n; 1995. 3 p. tab.
Descritores:DISTRIBUIÇAO DE QUI-QUADRADO
CROMATOGRAFIA LIQUIDA DE ALTA PRESSAO
CORTICOTROPINA
HIDROCORTISONA
HANSENIASE
Localização:BR191.1; 08331/s


  4 / 7 HANSEN  
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Id:14278
Autor:Kulkarni, H. R; Zodpey, S. P
Título:Differential protective effect of bacillus Calmette-Guerin vaccine against multibacillary and paucibacillary leprosy in Nagpur, India
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Fonte:s.l; s.n; 1999. 3 p. tab.
Descritores:ADOLESCENCIA
VACINA BCG
ESTUDOS DE CASOS E CONTROLES
DISTRIBUIÇAO DE QUI-QUADRADO
CRIANÇA
INTERVALOS DE CONFIANÇA
INDIA
HANSENIASE
HANSENIASE
HANSENIASE
ANALISE POR PAREAMENTO
RAZAO DE DIFERENÇA
CLASSE SOCIAL
Localização:BR191.1; 07173/s


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Id:14106
Autor:Zerva, Loukia; Cizman, Bojana; Mehra, Navinder K; Alahari, Souresh K; Murali, Ramachandran; Zmijewski, Chester M; Kamoun, Malek; Monos, Dimitri
Título:Arginine at positions 13 or 70-71 in pocket 4 of HLA-DRB1 alleles is associated with susceptibility to tuberculoid leprosy
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Fonte:s.l; s.n; 1996. 8 p. ilus, tab.
Descritores:ALELOS
SEQUENCIA DE AMINOACIDOS
ARGININA
DISTRIBUIÇAO DE QUI-QUADRADO
CRISTALOGRAFIA POR RAIOS X
SUSCETIBILIDADE A DOENÇA
GENES CLASSE II DO COMPLEXO DE HISTOCOMPATIBILIDADE (MHC)
ANTIGENOS HLA-DR
ANTIGENOS HLA-DR
TESTE DE HISTOCOMPATIBILIDADE
HANSENIASE TUBERCULOIDE
HANSENIASE TUBERCULOIDE
HANSENIASE TUBERCULOIDE
SISTEMAS MACROMOLECULARES
MODELOS MOLECULARES
DADOS DE SEQUENCIA MOLECULAR
REAÇAO EM CADEIA POR POLIMERASE
CONFORMAÇAO PROTÉICA
VALORES DE REFERENCIA
FATORES DE RISCO
Localização:BR191.1; 07048/s


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Id:13375
Autor:Lapinsky, S. E; Baynes, R. D; Schulz, E. J; Macphail, A. P; Mendelow, B; Lewis, D; Bothwell, T. H
Título:Anaemia, iron-related measurements and erythropoietin levels in untreated patients with active leprosy
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Fonte:s.l; s.n; 1992. 6 p. tab, graf.
Descritores:ANALISE DE VARIANCIA
ANEMIA HIPOCROMICA
ANEMIA HIPOCROMICA
MARCADORES BIOLOGICOS
DISTRIBUIÇAO DE QUI-QUADRADO
ERITROPOETINA
TESTES HEMATOLOGICOS
FERRO
HANSENIASE
HANSENIASE
HANSENIASE LEPROMATOSA
HANSENIASE LEPROMATOSA
Localização:BR191.1; 06418/s


  7 / 7 HANSEN  
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Id:13188
Autor:Rosero, Alicia Caiza; Gonzalez, Patricia Viana; Nery, Jose Augusto da Costa; Mendonca, Ignes Regina dos Santos Muri; Azulay, Rubem David
Título:Mal perfurante plantar: estudo de 50 casos
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Fonte:s.l; s.n; 1996. 4 p. ilus, tab.
Descritores:DEFORMIDADES ADQUIRIDAS DO PÉ
NEUROPATIAS DIABÉTICAS
HANSENIASE
ALCOOLISMO
ULCERA DO PÉ
DISTRIBUIÇAO DE QUI-QUADRADO
Localização:BR191.1; 06128/s



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